Cincinnati Children’s Undiagnosed and Rare Liver Disease Center(CURL)

Are you seeking a precise diagnosis for your rare liver disease, or a personalized plan of care for the unique aspects of your liver disease and treatment course?

Cincinnati Children’s Undiagnosed and Rare Liver Disease Center (CURL) is an integrated medical and research center, founded with a focus on progressive familial intrahepatic cholestasis (PFIC) and other rare or genetic liver diseases, with the goal to address unmet needs in the rare liver disease community.

CURL is integrated with Cincinnati Children’s state-of-the-art and nationally recognized research center and is comprised of physician-scientists with decades of clinical expertise at Cincinnati Children’s Division of Gastroenterology, Hepatology & Nutrition, ranked #1 by the 2022 US News & World Report. Our medical research team will review your unique pathology, genetic makeup, and clinical history and work to provide a precise diagnosis for those still seeking answers for their rare liver disease. We offer improved therapies for PFIC and other rare liver disease and the expertise to find innovative solutions for complications of the treatment and disease process. CURL offers consultation and second opinions on clinical plans of care for both adults and pediatric patients and is dedicated to help each patient achieve their unique care goals. 

Interested to be contacted by our medical research team? Sign up using our web link:

You may also inquire for an initial patient consultation or request more information regarding our center by sending an email to or calling 513-636-5706.

Learn more about liver care at Cincinnati Children’s:

Liver Care | Cincinnati Children’s (