PFIC Small Research Grant

Announcement of the 2021 PFIC Network

Small Grant Opportunity

Key Dates

Release Date: December 2021
Application Due Date: March 31st, 2022
Review: April 30th, 2022
Earliest Start Date: June 1st, 2022

Purpose

This announcement invites applications that focus on improving the post-diagnosis assessment of aspects of PFIC diseases including but not limited to (1) aspects and severity of pruritus, (2) secondary symptoms, (3) the psychological and emotional burden of PFIC diseases on patients and/or their caretakers, or (4) the socio-economic burden of PFIC diseases on patients and/or their caretakers. The purpose of this funding opportunity is to promote the development of assessment tools or the systematic and reliable assessment of these aspects with the aim to better understand the complex impact PFIC diseases have on patients and their caretakers.

Background

PFIC Network is committed to improving treatment options, slow disease progression, and ultimately finding a cure for PFIC diseases. The Small Grant Program is designed to contribute to this mission by funding research that leads to improvements in the lives of PFIC patients and their caretakers. The 2021 Small Grant Opportunity focusses on improving the assessment of aspects of PFIC diseases. Rigorous and reliable assessment is needed to facilitate the study of disease development and variability. Improved assessment can also support the development of a data base that permits the study of treatment response and that can contribute to the advancement of integrated treatment strategies.

Award Information

In this cycle PFIC Network will award one small grant with a budget limited to $30,000. The award period is one year. A virtual progress report meeting will be scheduled 6 months after the starting date, and a written study report detailing outcomes is expected after one year. PFIC Network invites applications for independent studies, pilot research, or studies that extend currently funded research.

Eligibility Information

Applicants are required to have a full-time position at an academic, non-profit, or government institution, and are required to have a PhD or a comparable certification. Individuals from historically underserved or underrepresented communities are encouraged to apply.

Application Submission

Required elements of an application include:

  • Research plan (4 page limitation)
    The research plan should include
    • a brief lay abstract
    • an overview of the background and study aim(s)
    • a research strategy describing the study design, methods, and planned analyses. In case the proposed research involves human subjects it is necessary to include the participant demographics, recruitment plan, and IRB approval from the applicant’s organization
    • deliverables describing the tangible results of the proposed study
  • Applicant biosketch (2 page limitation)
  • Budget

Review Process

Applications will be reviewed according to the following patient/caretaker and scientific criteria:

  • Relevance for PFIC Network’s mission and grant program
    • Will the application advance PFIC Networks mission to improve the lives of patients and families worldwide affected by PFIC? Does the application meet the purpose of the funding opportunity?
  • Benefit for PFIC patients and community
    • What are the short and/or long terms benefits of the proposed research for PFIC patients and families?
  • Burden for Study Participants
    • Are human subjects involved in this study? If so, are they appropriately protected from study risk? Does the study require lab data? Does study participation necessitate travel? Is the time burden for participants acceptable?
  • Scientific impact/innovation
    • Does the proposed research address an important problem? If the described goals are met, will the research lead to novel insights that may ultimately improve the lives of patients affected by PFIC?
  • Research Approach
    • If the study includes human subjects, are their demographics clearly described? Is the study design adequate to achieve the study goals? Are the theoretical background, the study design, and the planned analyses logically integrated? Are potential weaknesses identified and are alternative strategies included?
  • Applicant/Environment
    • Is the (principal) investigator adequately trained to carry out the proposed study? Is the time commitment of the applicant to the proposed study realistic? Is the environment in which the study will be carried out favorable to contribute to study success?
  • Budget
    • Is the budget realistic to achieve the proposed study goals?

Notification and Award Conditions

PFIC Network will notify all applicants electronically via email after the review cycle has concluded and an award decision has been made. The award funds will be disbursed upon receipt of the signed regulatory documents (“Terms and Conditions”).

Conditions: Terms and conditions can be found here. Compliance to terms and conditions is a condition for the disbursement of funds.

Questions and Additional Information
For any questions please email admin@pfic.org.

Progressive Familial Intrahepatic Cholestasis Advocacy and Resource Network, Inc. (PFIC Network, Inc.) is a registered non-profit organization with the mission to improve the lives of patients and families worldwide affected by PFIC.